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Lori Coble and her husbad lost their three children in a devastating traffic accident. The couple supported each other through an unimaginable tragedy, and years later had a new set of triplets through IVF. Now, Lori has announced the heartbreaking news that she\u2019s been diagnosed with Stage 4 brain cancer.<\/strong><\/p>\n In May 2007, Lori Coble and her husband, Chris, experienced a tragedy no one should ever have to endure. While standing still in traffic on the freeway on May 4, a big rig slammed into the back of her minivan.<\/p>\n In the car were Lori and Chris\u2019 three children \u2013 5-year-old Kyle Christopher, 4-year-old Emma Lynn, and 2-year-old Katie Gene. None of the children survived the crash, and life would never ever be the same.<\/p>\n The children were taken to different hospitals, and Lori was also injured. Emma and Katie died before Lori woke up. Chris then rushed Lori to the hospital where Kyle was being treated, but it was too late.<\/p>\n Chris recalled in in interview with Oprah<\/a>, \u201cShe\u2019s climbing out of the wheelchair the best she can to hug Kyle and saying: \u2018He\u2019s got to go be with his sisters now. His sisters are waiting for him.<\/p>\n \u201cWe stopped life support, and the machines went dark and the room went dark. I held my hand on his chest until his heart stopped beating. And he was gone,\u201d he added.<\/p>\n Lori and her husband decided to make a pact. Although their lives were completely destroyed, feeling there was no reason to live, they made a pact that they would ot end their lives and instead support each other fully throughout the traumatic experience.<\/p>\n As they mourned their children, they felt they wanted to be parents again. Although Chris had had a vasectomy, they pursued IVF. Not long after, they saw three viable embryos: two girls and one boy, just like their three late children.<\/p>\n A year after the death of Kyle, Emma and Katie passed away, and Chris and Lori welcomed their triplets.<\/p>\n \u201cIt took me over four years to come out of the fog and pain of what happened. The first three years of raising the triplets you have this mix of joy and happiness, and at the same time, you\u2019re in pain on the inside, Chris told People Magazine<\/a>.<\/p>\n \u201cThere\u2019s these three babies and they\u2019re all joy\u2026. But at the same time, I was trying to avoid falling apart in front of them, I\u2019d go into the other room and cry real quick and come back and put a smile on my face.\u201d<\/p>\n A family friend, Becky Leonard, said about Lori, \u201cShe is extraordinary \u2014 everybody who knows her, loves her. First and foremost, she\u2019s a mom.\u201d<\/p>\n The Coble family has gone through an experience that\u2019s hard to put into words. And now, another heartbreak has struck. In June 2025, Chris noticed that Lori was \u201cgetting more clumsy,\u201d as she often dropped glasses on the floor, stubbed her toes on chairs, and so on.<\/p>\n Some weeks later, he noticed she had stroke-like symptoms as her \u201cmouth started to droop a little bit.\u201d It became \u201ctoo much to ignore.\u201d<\/p>\n In mid-July, Lori Coble was diagnosed with a large, very aggressive, stage 4 glioblastoma, brain cancer.<\/p>\n![\"Credit:](\"https:\/\/cdn-main.newsner.com\/wp-content\/uploads\/sites\/11\/2026\/01\/08083215\/coblechildren.jpg\")
Lori Coble and husband Chris welcomed triplets after their children died in car crash<\/h2>\n
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Lori was diagnosed with stage 4 brain cancer<\/h2>\n
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